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15 August 2008

Volume 47, Number 4
Clinical Infectious Diseases 2008;47:e39–e41
1058-4838/2008/4704-00E1$15.00
DOI: 10.1086/590250
BRIEF REPORT

Febrile Plasmodium falciparum Malaria 4 Years after Exposure in a Man with Sickle Cell Disease

Tatiana Greenwood,1

Tomas Vikerfors,2

Maria Sjöberg,2

Gunnar Skeppner,1 and

Anna Färnert3

Departments of 1Pediatrics and 2Infectious Diseases, Örebro University Hospital, Örebro, and 3Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

We report a case of symptomatic Plasmodium falciparum malaria that manifested 4 years after a visit to an area of endemicity in an 18‐year‐old male patient with sickle cell disease. The exceptionally long incubation time raises the questions of how and where P. falciparum parasites can reside for several years before suddenly causing disease.

Received 18 February 2008; accepted 21 March 2008; electronically published 10 July 2008.

Reprints or correspondence: Dr. Tatiana Greenwood, Dept. of Pediatrics, Örebro University Hospital, SE‐70185 Örebro, Sweden ().
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