Secondary Syphilis with Ocular Manifestations in Older Adults
1United States Naval Medical Research Center Detachment, Lima, Peru; and Departments of 2Medicine and 3Pathology, University of California San Diego, and 4Veterans Administration San Diego Healthcare System, San Diego, California
We describe 4 patients (age, >50 years) with secondary syphilis. All patients presented with ocular syphilis, and 2 presented with syphilis‐negative rapid plasma reagin titers due to a prozone phenomenon. Three male patients reported sildenafil use. The presentation of these patients with ocular syphilis suggests the need for additional clinical studies involving older patients.
Received 26 December 2007; accepted 1 February 2008; electronically published 5 May 2008.
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Online publication date: 1-Jan-2009.
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The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, Department of Veterans Affairs, or the US Government. R.C.M. and J.F. are employees of the U.S. Government. This work was prepared as part of their official duties. Title 17 U.S.C. §105 provides that Copyright protection under this title is not available for any work of the United States Government. Title 17 U.S.C. §101 defines a U.S. Government work as a work prepared by a military service member or employee of the U.S. Government as part of that person’s official duties.



