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15 June 2008

Volume 46, Number 12
Clinical Infectious Diseases 2008;46:e142–e145
1058-4838/2008/4612-00E3$15.00
DOI: 10.1086/588483
BRIEF REPORT

Secondary Syphilis with Ocular Manifestations in Older Adults

Ryan C. Maves,1

Edward R. Cachay,2

Maile Ann Young,2 and

Joshua Fierer2,3,4

1United States Naval Medical Research Center Detachment, Lima, Peru; and Departments of 2Medicine and 3Pathology, University of California San Diego, and 4Veterans Administration San Diego Healthcare System, San Diego, California

We describe 4 patients (age, >50 years) with secondary syphilis. All patients presented with ocular syphilis, and 2 presented with syphilis‐negative rapid plasma reagin titers due to a prozone phenomenon. Three male patients reported sildenafil use. The presentation of these patients with ocular syphilis suggests the need for additional clinical studies involving older patients.

Received 26 December 2007; accepted 1 February 2008; electronically published 5 May 2008.

Reprints or correspondence: Dr. Ryan Maves, Naval Medical Research Center Detachment, Unit 3800, APO AA 34031 USA ().

Cited by

M. Pleimes, W. Hartschuh, H. Kutzner, A. H. Enk, and M. Hartmann. (2009) Malignant Syphilis with Ocular Involvement and Organism‐Depleted Lesions. Clinical Infectious Diseases 48:1, 83-85
Online publication date: 1-Jan-2009.
  • The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, Department of Veterans Affairs, or the US Government. R.C.M. and J.F. are employees of the U.S. Government. This work was prepared as part of their official duties. Title 17 U.S.C. §105 provides that Copyright protection under this title is not available for any work of the United States Government. Title 17 U.S.C. §101 defines a U.S. Government work as a work prepared by a military service member or employee of the U.S. Government as part of that person’s official duties.

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