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15 June 2008

Volume 46, Number 12
Clinical Infectious Diseases 2008;46:1881–1883
1058-4838/2008/4612-0012$15.00
DOI: 10.1086/588476
BRIEF REPORT

Impact of Lactoferrin Supplementation on Growth and Prevalence of Giardia Colonization in Children

Theresa J. Ochoa,1,2

Elsa Chea‐Woo,1

Miguel Campos,1

Iris Pecho,1

Ana Prada,1

Robert J. McMahon,3 and

Thomas G. Cleary2

1Universidad Peruana Cayetano Heredia, Lima, Peru; 2Center for Infectious Diseases, University of Texas School of Public Health, Houston; and 3Mead Johnson Nutritionals, Evansville, Indiana

We conducted a randomized, double‐blind, placebo‐controlled trial comparing supplementation with bovine lactoferrin versus placebo for the prevention of diarrhea in children. Comparison of overall diarrhea incidence and prevalence rates found no significant difference between the 2 groups. However, there was a lower prevalence of colonization with Giardia species and better growth among children in the lactoferrin group.

Received 3 December 2007; accepted 23 February 2008; electronically published 5 May 2008.

Reprints or correspondence: Dr. Theresa J. Ochoa, Instituto de Medicina Tropical, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, San Martin de Porras, Lima 33, Peru ().

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