Enhanced Fe Ion–Uptake Activity in Helicobacter pylori Strains Isolated from Patients with Iron‐Deficiency Anemia
1Department of Microbiology, Sapporo Medical University School of Medicine, and 2Department of Pediatrics, Sapporo Kosei General Hospital, Sapporo, Japan
Recent studies have suggested a link between iron‐deficiency anemia and Helicobacter pylori infection. In the current study, strains of H. pylori derived from patients with iron‐deficiency anemia showed enhanced Fe ion uptake and Fe ion–dependent rapid growth compared with those from patients with non–iron‐deficiency anemia. H. pylori with enhanced Fe ion–uptake ability may be a causative factor for iron‐deficiency anemia.
Received 26 August 2007; accepted 31 October 2007; electronically published 15 January 2008.
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