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15 February 2008

Volume 46, Number 4
Clinical Infectious Diseases 2008;46:e31–e33
1058-4838/2008/4604-00E1$15.00
DOI: 10.1086/526784
BRIEF REPORT

Enhanced Fe Ion–Uptake Activity in Helicobacter pylori Strains Isolated from Patients with Iron‐Deficiency Anemia

Shin‐ichi Yokota,1

Mutsuko Konno,2

Emi Mino,2

Kohei Sato,2

Michiko Takahashi,2 and

Nobuhiro Fujii1

1Department of Microbiology, Sapporo Medical University School of Medicine, and 2Department of Pediatrics, Sapporo Kosei General Hospital, Sapporo, Japan

Recent studies have suggested a link between iron‐deficiency anemia and Helicobacter pylori infection. In the current study, strains of H. pylori derived from patients with iron‐deficiency anemia showed enhanced Fe ion uptake and Fe ion–dependent rapid growth compared with those from patients with non–iron‐deficiency anemia. H. pylori with enhanced Fe ion–uptake ability may be a causative factor for iron‐deficiency anemia.

Received 26 August 2007; accepted 31 October 2007; electronically published 15 January 2008.

Reprints or correspondence: Dr. Mutsuko Konno, Dept. of Pediatrics, Sapporo Kosei General Hospital, North‐3, East‐8, Chuo‐ku, Sapporo 060–0033, Japan ().

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