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1 February 2008

Volume 46, Number 3
Clinical Infectious Diseases 2008;46:440–442
1058-4838/2008/4603-0013$15.00
DOI: 10.1086/524695
BRIEF REPORT

Early Sequential Development of Infective Dermatitis, Human T Cell Lymphotropic Virus Type 1–Associated Myelopathy, and Adult T Cell Leukemia/Lymphoma

Lourdes Farre,1

Maria de Fátima Paim de Oliveira,2

Janeusa Primo,2

Anne‐Mieke Vandamme,4

Johan Van Weyenbergh,1 and

Achiléa L. Bittencourt3

1Laboratory of Immunoregulation and Microbiology, Centro de Pesquisa Conçalo Moniz–Fundação Oswaldo Cruz, and Departments of 2Internal Medicine and 3Pathology, Hospital Universitário Prof. Edgard Santos, Federal University of Bahia, Bahia, Brazil; and 4Clinical and Epidemiological Virology, Rega Institute, Katholieke Universiteit, Leuven, Belgium

We describe a patient with human T cell lymphotropic virus type 1 (HTLV‐1)–associated infective dermatitis who developed HTLV‐1–associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.

Received 24 July 2007; accepted 23 August 2007; electronically published 3 January 2008.

Reprints or correspondence: Dr. Lourdes Farre, D, Laboratory of Immunoregulation and Microbiology, CPqGM‐FIOCRUZ, Rua Waldemar Falcão 121, Brotas, Salvador 40295001, Bahia, Brazil ().

Cited by

Luciana Maragno, Jorge Casseb, Ligia Maria I. Fukumori, Mirian Nacagami Sotto, Alberto José da Silva Duarte, Cyro Festa-Neto, José Antônio Sanches. (2009) Human T-cell lymphotropic virus type 1 infective dermatitis emerging in adulthood. International Journal of Dermatology 48:7, 723-730
Online publication date: 1-Aug-2009.
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