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1 November 2007

Volume 45, Number 9
Clinical Infectious Diseases 2007;45:1214–1220
1058-4838/2007/4509-0016$15.00
DOI: 10.1086/522180
HIV/AIDS INVITED ARTICLE

Coinfection with HIV and Tropical Infectious Diseases. II. Helminthic, Fungal, Bacterial, and Viral Pathogens

Christopher L. Karp1 and

Paul G. Auwaerter2

1Division of Molecular Immunology, Cincinnati Children’s Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio, and 2Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland

The morbidity, mortality, and social disruption caused by the human immunodeficiency virus (HIV) pandemic continue to weigh disproportionately on resource‐poor regions of the tropics. As a result, the potential for significant epidemiological, biological, and clinical interactions between HIV and other tropical pathogens is great. An overview of the available data on tropical helminths, fungi, bacteria, and viruses is provided here; interactions between HIV and tropical protozoa are covered in a related mini‐review in this issue of Clinical Infectious Diseases. Special attention is given to evidence relevant to the hypothesis that helminth coinfection plays a particularly important role in accelerating the pace of HIV pathogenesis in the tropics.

Received 19 April 2007; accepted 7 July 2007; electronically published 21 September 2007.

Reprints or correspondence: Dr. C. L. Karp, Div. of Molecular Immunology, Cincinnati Children’s Hospital Research Foundation, 3333 Burnet Ave., Cincinnati, OH 45229 ().

Kenneth H. Mayer, Section Editor

Cited by

Christopher L. Karp and Paul G. Auwaerter. (2007) HIV/AIDS: Coinfection with HIV and Tropical Infectious Diseases. I. Protozoal Pathogens. Clinical Infectious Diseases 45:9, 1208-1213
Online publication date: 1-Nov-2007.
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