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NHSN Annual Update:
Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections

Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007

Antimicrobial-resistant pathogens that cause healthcare-associated infections (HAIs) pose an ongoing and increasing challenge to hospitals, both in the clinical treatment of patients and in the prevention of the cross-transmission of these problematic pathogens.  Describing the magnitude of the problem with respect to these antimicrobial-resistant pathogens is challenging, because the levels of antimicrobial resistance vary for different types of healthcare facilities and for different geographic areas, and some resistance phenotypes are difficult for laboratories to detect. However, the findings from such attempts may help the infection control and public health communities target problems and utilize resources more efficiently.

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Fidelma Fitzpatrick, MD; Fiona Roche, PhD; Robert Cunney, MB; Hilary Humphreys, MD; Strategy for the Control of Antimicrobial Resistance in Ireland Infection Control Subcommittee
The research, published in Infection Control and Hospital Epidemiology, found one third of hospitals did not have a written policy on antibiotic use, and only 35% had an antibiotic stewardship programme.

July 2007

Volume 28, Number 7
Infect Control Hosp Epidemiol 2007;28:791–798
0899-823X/2007/2807-0004$15.00
DOI: 10.1086/518453
Original Article

Effectiveness of Multifaceted Hospitalwide Quality Improvement Programs Featuring an Intervention to Remove Unnecessary Urinary Catheters at a Tertiary Care Center in Thailand

Anucha Apisarnthanarak, MD;

Kanokporn Thongphubeth, RN;

Sirinaj Sirinvaravong, MD;

Danai Kitkangvan, MD;

Chananart Yuekyen, RN;

Boonyasit Warachan, PhD;

David K. Warren, MD;

Victoria J. Fraser, MD

From the Divisions of Infectious Diseases and Infection Control (A.A., K.T., C.Y.) and Internal Medicine (S.S., D.K.), Faculty of Medicine, Thammasart University Hospital, Pratumthani, and the Department of Applied Statistics, Faculty of Science, King Mongkut’s Institute of Technology, Ladkrabang, Bangkok (B.W.), Thailand; and the Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri (D.K.W., V.J.F.).

Objective.To evaluate the efficacy of a multifaceted hospitalwide quality improvement program that featured an intervention to remind physicians to remove unnecessary urinary catheters.

Methods.A hospitalwide preintervention‐postintervention study was conducted over 2 years (July 1, 2004, through June 30, 2006). The intervention consisted of nurse‐generated daily reminders that were used by an intervention team to remind physicians to remove unnecessary urinary catheters, beginning 3 days after insertion. Clinical, microbiological, pharmaceutical, and cost data were collected.

Results.A total of 2,412 patients were enrolled in the study. No differences were found in the demographic and/or clinical characteristics of patients between the preintervention and postintervention periods. After the intervention, reductions were found in the rate of inappropriate urinary catheterization (mean rate, preintervention vs postintervention, 20.4% vs 11% [ ]), the rate of catheter‐associated urinary tract infection (CA‐UTI) (mean rate, 21.5 vs 5.2 infections per 1,000 catheter‐days [ ]), the duration of urinary catheterization (mean, 11 vs 3 days [ ]), and the total length of hospitalization (mean, 16 vs 5 days [ ]). A linear relationship was seen between the monthly average duration of catheterization and the rate of CA‐UTI ( ; ). The intervention had the greatest impact on the rate of CA‐UTI in the intensive care units (mean rate, preintervention vs postintervention, 23.4 vs 3.5 infections per 1,000 catheter‐days [ ]). The monthly hospital costs for antibiotics to treat CA‐UTI were reduced by 63% (mean, $3,739 vs $1,378 [ ]), and the hospitalization cost for each patient during the intervention was reduced by 58% (mean, $366 vs $154 [ ]).

Conclusions.This study suggests that a multifaceted intervention to remind physicians to remove unnecessary urinary catheters can significantly reduced the duration of urinary catheterization and the CA‐UTI rate in a hospital in a developing country.

Received September 13, 2006; accepted December 1, 2006; electronically published May 31, 2007.

Address reprint requests to Anucha Apisarnthanarak, MD, Division of Infectious Diseases, Faculty of Medicine, Thammasart University Hospital, Pratumthani, Thailand 12120 ().

Cited by

Anucha Apisarnthanarak and Victoria J. Fraser. (2009) Editorial Commentary: Feasibility and Efficacy of Infection‐Control Interventions to Reduce the Number of Nosocomial Infections and Drug‐Resistant Microorganisms in Developing Countries: What Else Do We Need?. Clinical Infectious Diseases 48:1, 22-24
Online publication date: 1-Jan-2009.
Paola Lichtenberger, Thomas M. Hooton. (2008) Complicated urinary tract infections. Current Infectious Disease Reports 10:6, 499-504
Online publication date: 1-Dec-2008.
CrossRef
Anucha Apisarnthanarak, MD; Akeruetai Suwannakin, MD; Puritat Maungboon, MD; David K. Warren, MD; Victoria J. Fraser, MD. (2008) Long‐Term Outcome of an Interventionto Remove Unnecessary Urinary Catheters, With and Without a Quality Improvement Team, in a Thai Tertiary Care Center •. Infection Control and Hospital Epidemiology 29:11, 1094-1095
Online publication date: 1-Nov-2008.
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