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1 May 2007

Volume 195, Number 9
The Journal of Infectious Diseases 2007;195:1278–1282
© 2007 by the Infectious Diseases Society of America. All rights reserved.
0022-1899/2007/19509-0008$15.00
DOI: 10.1086/513274
BRIEF REPORT

HIV and Parasitic Infection and the Effect of Treatment among Adult Outpatients in Malawi

Mina C. Hosseinipour,1,2

Sonia Napravnik,2

George Joaki,1

Syze Gama,1

Nyanyiwe Mbeye,1

Blessings Banda,1

Francis Martinson,1

Irving Hoffman,2 and

Myron S. Cohen2

1University of North Carolina Project, Lilongwe, Malawi; 2University of North Carolina at Chapel Hill, Chapel Hill

We measured enteric parasitic infection prevalence and the effect of treatment on human immunodeficiency virus (HIV) RNA levels to assess their importance to HIV primary care in resource‐limited settings. Adults in Lilongwe, Malawi, were evaluated, treated, and followed‐up for parasitic and HIV infections. Of 389 patients, 266 (68%) were HIV infected. Helminth infections were more common in HIV‐uninfected than in HIV‐infected patients (39% vs. 17%). Among HIV‐infected patients, helminth infections were associated with higher CD4 cell counts but not with higher HIV RNA levels. Successful treatment of parasitic infections had no effect on HIV RNA levels. Although common, parasitic infections did not impact HIV RNA levels.

Received 4 August 2006; accepted 24 November 2006; electronically published 20 March 2007.

Reprints or correspondence: Dr. Mina Hosseinipour, Div. of Infectious Diseases, Bioinformatics Bldg., 130 Mason Farm Rd., Campus Box 7030, Chapel Hill, NC 27599‐7030 ().

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  • Potential conflicts of interest: none reported.

    Financial support: National Institutes of Health (NIH; grant P30 AI 50410 to fund the Center for AIDS Research program at the University of North Carolina at Chapel Hill); NIH Fogarty Center Career Development Award (National Institute of Allergy and Infectious Diseases grant 1 K01 TW06677‐01 to M.C.H.).

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