Yellow Fever: Epidemiology and Prevention
Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston, Massachusetts
Yellow fever continues to occur in regions of Africa and South America, despite the availability of effective vaccines. Recently, some cases of severe neurologic disease and multiorgan system disease have been described in individuals who received yellow fever vaccine. These events have focused attention on the need to define criteria for judicious use of yellow fever vaccine and to describe the spectrum of adverse events that may be associated with yellow fever vaccine. Describing host factors that would increase risk of these events and identifying potential treatment modalities for yellow fever and yellow fever vaccine–associated adverse events are subjects of intense investigation.
Received 15 September 2006; accepted 20 November 2006; electronically published 1 February 2007.
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Online publication date: 15-Dec-2007.



