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1 February 2007

Volume 44, Number 3
Clinical Infectious Diseases 2007;44:459–461
1058-4838/2007/4403-0027$15.00
DOI: 10.1086/510747
HIV/AIDS BRIEF REPORT

Screening for Acute HIV Infection: Lessons Learned

Joanne Stekler,1,4

Janine Maenza,1

Claire E. Stevens,1

Paul D. Swenson,5

Robert W. Coombs,1,2,4

Robert W. Wood,1,4,5

Mary S. Campbell,1

David C. Nickle,3,4

Ann C. Collier,1,4 and

Matthew R. Golden1,4,5

Departments of 1Medicine, 2Laboratory Medicine, and 3Microbiology, and 4Center for AIDS and STDs, University of Washington, and 5Public Health–Seattle & King County, Seattle, Washington

Human immunodeficiency virus (HIV) nucleic acid testing is increasingly being used by researchers and public health screening programs to identify highly infectious, HIV antibody–negative individuals with acute HIV infection. We present cases to illustrate unusual instances of acute HIV screening, which include “window period” testing and the discovery of low‐level HIV RNA.

Received 11 August 2006; accepted 27 September 2006; electronically published 20 December 2006.

Reprints and correspondence: Dr. Joanne Stekler, Box 359931, Harborview Medical Center, 325 9th Ave., Seattle, WA 98104 ().

Cited by

Joanne D. Stekler, Paul D. Swenson, Robert W. Coombs, Joan Dragavon, Katherine K. Thomas, Catherine A. Brennan, Sushil G. Devare, Robert W. Wood, and Matthew R. Golden. (2009) HIV Testing in a High‐Incidence Population: Is Antibody Testing Alone Good Enough?. Clinical Infectious Diseases 49:3, 444-453
Online publication date: 1-Aug-2009.
Donna J Helms, Hillard S Weinstock, Kristen C Mahle, Kyle T Bernstein, Bruce W Furness, Charlotte K Kent, Cornelis A Rietmeijer, Akbar M Shahkolahi, James P Hughes, Matthew R Golden. (2009) HIV Testing Frequency Among Men Who Have Sex With Men Attending Sexually Transmitted Disease Clinics: Implications for HIV Prevention and Surveillance. JAIDS Journal of Acquired Immune Deficiency Syndromes 50:3, 320-326
Online publication date: 1-Apr-2009.
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Matthew R Golden, Joanne Stekler, James P Hughes, Robert W Wood. (2008) HIV Serosorting in Men Who Have Sex With Men: Is It Safe?. JAIDS Journal of Acquired Immune Deficiency Syndromes 49:2, 212-218
Online publication date: 1-Nov-2008.
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Raúl Ortiz de Lejarazu, Vincent Soriano, José M. Eiros, Manuel Arias, and Carlos Toro. (2008) HIV‐1 Infection in Persistently HIV‐1–Seronegative Individuals: More Reasons for HIV RNA Screening. Clinical Infectious Diseases 46:5, 785-785
Online publication date: 1-Mar-2008.
Sushil G. Devare. (2007) Early diagnosis of HIV infection. Journal of Medical Virology 79:S1, S11-S15
Online publication date: 1-Feb-2007.
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