Infect Control Hosp Epidemiol 2006;27:1120–1122
© 2006 by The Society for Healthcare Epidemiology of America. All rights reserved.
0899-823X/2006/2710-0017$15.00
DOI: 10.1086/507966
Concise Communication
Use of Gaseous Ozone for Eradication of Methicillin‐Resistant Staphylococcus aureus From the Home Environment of a Colonized Hospital Employee
Hero E. L. de Boer, MD;
Carla M. van Elzelingen‐Dekker, BSc;
Cora M. F. van Rheenen‐Verberg, BSc;
Lodewijk Spanjaard, MD, PhD
From the Departments of Occupational Health (H.E.L.d.B) and Medical Microbiology (C.M.v.E.‐D., C.M.F.v.R.‐V., L.S.), Academic Medical Center, Amsterdam, The Netherlands.
An intensive care nurse with eczema was repeatedly treated for methicillin‐resistant Staphylococcus aureus (MRSA) carriage. Because cultures remained positive for MRSA, her house was investigated. Thirty‐four percent of environmental samples yielded MRSA. Her children and cat were free of MRSA. The house was decontaminated with gaseous ozone. All subsequent cultures were negative for MRSA. This decontamination cost €2,000 (approximately $2,400).
Received March 18, 2005; accepted March 18, 2006; electronically published September 21, 2006.
Address reprint requests to Lodewijk Spanjaard, MD, PhD, Laboratory of Bacteriology, Academic Medical Center, L‐1‐243, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands (
L.Spanjaard@amc.uva.nl).
Cited by
John M. Boyce, MD. (2009)
Commentary: New Approaches to Decontamination of Rooms After Patients Are Discharged •

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Infection Control and Hospital Epidemiology 30:6, 515-517
Online publication date: 1-Jun-2009.
S. Burgassi, I. Zanardi, V. Travagli, E. Montomoli, V. Bocci. (2009) How much ozone bactericidal activity is compromised by plasma components?.
Journal of Applied Microbiology 106:5, 1715-1721
Online publication date: 1-Jun-2009.
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Staphylococcus aureus
ST30-IVc in Copenhagen, Denmark through an effective search and destroy policy.
Clinical Microbiology and Infection Online publication date: 1-Jun-2009.
CrossRef N. Cimolai. (2008) MRSA and the environment: implications for comprehensive control measures.
European Journal of Clinical Microbiology & Infectious Diseases 27:7, 481-493
Online publication date: 1-Aug-2008.
CrossRef Edina Avdic, Sara E Cosgrove. (2008) Management and control strategies for community-associated methicillin-resistant
Staphylococcus aureus.
Expert Opinion on Pharmacotherapy 9:9, 1463-1479
Online publication date: 1-Jul-2008.
CrossRef