All Journals > Clinical Infectious Diseases > 15 October 2006 > Pyomyositis and Myositis in Children

Article Tools

Search for Related Articles

  • By Author
  • Search In

Announcements

CID LISTED AMONG
“MOST INFLUENTIAL”

Clinical Infectious Diseases has been named as one of the "100 Most Influential Journals in Biology and Medicine" of the past 100 years by the Special Libraries Association. The list was compiled by the 680-plus members of SLA’s Biomedical and Life Sciences Division.

See the full list here.

Source: The DBIO 100, the 100 Most Influential Journals in Biology & Medicine over the last 100 Years

In the News

Featured in MSNBC
"Germs and flu are up; infection control is down" June 9, 2009
Trends in the Incidence of Methicillin‐Resistant Staphylococcus aureus Infection in Children’s Hospitals in the United States
Jeffrey S. Gerber, Susan E. Coffin, Sarah A. Smathers, and Theoklis E. Zaoutis
Just this week, researchers reported that the incidence of MRSA infections among children admitted to pediatric hospitals in the United States more than tripled between 2002 and 2007. Researchers at the Children’s Hospital of Philadelphia and the University of Pennsylvania found cases of MRSA jumped from 6.7 per 1,000 admissions in 2002 to 21.1 cases per 1,000 admissions in 2007, according to a study released online Monday in the journal Clinical Infectious Diseases.

Featured in Toronto Star
"Pigs, viruses and politics" May 2, 2009
Are Swine Workers in the United States at Increased Risk of Infection with Zoonotic Influenza Virus?
Kendall P. Myers, Christopher W. Olsen, Sharon F. Setterquist, Ana W. Capuano, Kelley J. Donham, Eileen L. Thacker, James A. Merchant, and Gregory C. Gray
Another study, this one published in the U.S. journal Clinical Infectious Diseases in 2006, found that workers in meat-processing plants have a greater likelihood of being infected by some version of the H1N1 flu virus than the general population (the odds of pig farmers getting the disease are significantly greater again).

Featured in Philadelphia Inquirer
"A shot in the arm for vaccines" April 19, 2009
Vaccines: Pneumococcal Vaccination of Elderly Adults: New Paradigms for Protection
Lisa A. Jackson and Edward N. Janoff
Every year, an estimated 915,000 people 65 and older get pneumonia, and 40 percent of them end up in hospitals, according to a 2004 paper in the journal Clinical Infectious Diseases. Pneumonia often kills older people, said Richard Stefanacci, a geriatrician at the University of the Sciences in Philadelphia.

15 October 2006

Volume 43, Number 8
Clinical Infectious Diseases 2006;43:953–960
© 2006 by the Infectious Diseases Society of America. All rights reserved.
1058-4838/2006/4308-0001$15.00
DOI: 10.1086/507637
MAJOR ARTICLE

Infective Pyomyositis and Myositis in Children in the Era of Community‐Acquired, Methicillin‐Resistant Staphylococcus aureus Infection

Pia S. Pannaraj,

Kristina G. Hulten,

Blanca E. Gonzalez,

Edward O. Mason, Jr., and

Sheldon L. Kaplan

Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas

Background.Cases of pyomyositis and myositis have been increasing in frequency at Texas Children’s Hospital (Houston) since 2000. The increase appears to correlate with the emergence of community‐acquired methicillin‐resistant Staphylococcus aureus (MRSA).

Methods.The medical records of patients with pyomyositis and myositis hospitalized at Texas Children’s Hospital during the period from January 2000 through December 2005 were reviewed. Available S. aureus isolates were obtained for susceptibility testing, to determine the presence of pvl (lukS‐PV and lukF‐PV), and for pulsed‐field gel electrophoresis analysis.

Results.Forty‐five previously healthy children with bacterial pyomyositis or myositis were analyzed. The causes were S. aureus (in 57.8% of children) and Streptococcus pyogenes (in 2.2%); 40.0% of children had negative culture results. The number of cases increased between 2000 and 2005, primarily as a result of an increase in the prevalence of community‐acquired MRSA. The mean patient age was 5.5 years (range, 0.06–15 years). The thigh (40.0% of children) and pelvis (28.9%) were the most commonly affected sites. The mean abscess diameter was 3.5 cm. Eighteen children required at least 1 muscle drainage procedure. Of the 24 available S. aureus isolates (15 community‐acquired MRSA isolates and 9 community‐acquired, methicillin‐susceptible S. aureus [MSSA] isolates), 16 were found to be USA300 by pulsed‐field gel electrophoresis, and 17 carried pvl. Patients with community‐acquired MRSA, USA300, and/or pvl‐positive strains required more drainage procedures than did those with community‐acquired MSSA, non‐USA300, and/or pvl‐negative strains (81% vs. 40% [ ], 82% vs. 29% [ ], and 81% vs. 38% [ ], respectively).

Conclusions.Community‐acquired MRSA is an increasing cause of pyomyositis and myositis in children. Community‐acquired MRSA, USA300, pvl‐positive S. aureus isolates caused more severe disease than did community‐acquired MSSA, non‐USA300, and pvl‐negative isolates, respectively.

Received 14 April 2006; accepted 16 June 2006; electronically published 1 September 2006.

Reprints or correspondence: Dr. Pia S. Pannaraj, Dept. of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Rm. 302A, Houston, TX 77030 ().

Cited by

GEORGE Y. LIU. (2009) Molecular Pathogenesis of Staphylococcus aureus Infection. Pediatric Research 65:Supplement, 71R-77R
Online publication date: 1-Jun-2009.
CrossRef
Mukesh Patel. (2009) Community-Associated Meticillin-Resistant Staphylococcus aureus Infections. Drugs 69:6, 693-716
Online publication date: 1-Feb-2009.
CrossRef
Bruce M. Lo, Benjamin A. Fickenscher. (2009) Primary pyomyositis caused by ca-MRSA. International Journal of Emergency Medicine 1:4, 331-332
Online publication date: 1-Jan-2009.
CrossRef
Y.-C. Huang, C.-F. Ho, C.-J. Chen, L.-H. Su, T.-Y. Lin. (2009) Comparative molecular analysis of community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus isolates from children in northern Taiwan. Clinical Microbiology and Infection 14:12, 1167-1172
Online publication date: 1-Jan-2009.
CrossRef
Sheldon L. Kaplan. (2008) COMMENTARY: PREVENTION OF RECURRENT STAPHYLOCOCCAL INFECTIONS. The Pediatric Infectious Disease Journal 27:10, 935-937
Online publication date: 1-Nov-2008.
CrossRef
Blanca E. Gonzalez, Sheldon L. Kaplan. (2008) Severe Staphylococcal Infections in Children. Pediatric Annals 37:10, 686-693
Online publication date: 1-Nov-2008.
CrossRef
A. Ramos, L. Ley, E. Muñez, A. Videl, I. Sánchez. (2008) Brain Abscess due to Panton–Valentine Leukocidin-Positive Staphylococcus aureus. Infection
Online publication date: 25-Sep-2008.
CrossRef
Lorna P. Browne, Edward O. Mason, Sheldon L. Kaplan, Christopher I. Cassady, Rajesh Krishnamurthy, R. Paul Guillerman. (2008) Optimal imaging strategy for community-acquired Staphylococcus aureus musculoskeletal infections in children. Pediatric Radiology 38:8, 841-847
Online publication date: 1-Sep-2008.
CrossRef
Michelle J. Sunga, Sy Teisan, Ginger Tsueng, Venkat R. Macherla, Kin S. Lam. (2008) Seawater requirement for the production of lipoxazolidinones by marine actinomycete strain NPS8920. Journal of Industrial Microbiology & Biotechnology 35:7, 761-765
Online publication date: 1-Aug-2008.
CrossRef
Edina Avdic, Sara E Cosgrove. (2008) Management and control strategies for community-associated methicillin-resistant Staphylococcus aureus. Expert Opinion on Pharmacotherapy 9:9, 1463-1479
Online publication date: 1-Jul-2008.
CrossRef
Helen W. Boucher and G. Ralph Corey. (2008) Epidemiology of Methicillin‐Resistant Staphylococcus aureus. Clinical Infectious Diseases 46:s5, S344-S349
Online publication date: 1-Jun-2008.
Abstract-Full Text-PDF Version (367 kB)
Martin E. Stryjewski and Henry F. Chambers. (2008) Skin and Soft‐Tissue Infections Caused by Community‐Acquired Methicillin‐Resistant Staphylococcus aureus. Clinical Infectious Diseases 46:s5, S368-S377
Online publication date: 1-Jun-2008.
Abstract-Full Text-PDF Version (279 kB)
Michael Z. David, Daniel Glikman, Susan E. Crawford, Jie Peng, Kimberly J. King, Mark A. Hostetler, Susan Boyle‐Vavra, and Robert S. Daum. (2008) What Is Community‐Associated Methicillin‐Resistant Staphylococcus aureus?. The Journal of Infectious Diseases 197:9, 1235-1243
Online publication date: 1-May-2008.
Abstract-Full Text-PDF Version (158 kB)
Louis B. Rice, John G. Bartlett, Donald E. Craven, Dennis L. Stevens, Robert C. Moellering, George M. Eliopoulos. (2008) Emerging Treatments for Resistant Bacterial Infections and Pathogen-Focused Therapy. Infectious Diseases in Clinical Practice 16:Suppl. 1, S1-S20
Online publication date: 1-Apr-2008.
CrossRef
Loren G. Miller and Binh An Diep. (2008) Clinical Practice: Colonization, Fomites, and Virulence: Rethinking the Pathogenesis of Community‐Associated Methicillin‐Resistant Staphylococcus aureus Infection. Clinical Infectious Diseases 46:5, 752-760
Online publication date: 1-Mar-2008.
Abstract-Full Text-PDF Version (349 kB)
Brendan J. Kilbane, Sally L. Reynolds. (2008) Emergency Department Management of Community-Acquired Methicillin-Resistant Staphylococcus aureus. Pediatric Emergency Care 24:2, 109-114
Online publication date: 1-Mar-2008.
CrossRef
Jason G Newland, Gregory L Kearns. (2008) Treatment Strategies for Methicillin-Resistant Staphylococcus aureus Infections in Pediatrics. Pediatric Drugs 10:6, 367-378
Online publication date: 1-Feb-2008.
CrossRef
Rachel J. Gorwitz. (2008) A Review of Community-Associated Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections. The Pediatric Infectious Disease Journal 27:1, 1-7
Online publication date: 1-Feb-2008.
CrossRef
Rachel J. Gorwitz. (2008) Understanding the Success of Methicillin‐Resistant Staphylococcus aureus Strains Causing Epidemic Disease in the Community. The Journal of Infectious Diseases 197:2, 179-182
Online publication date: 15-Jan-2008.
Citation-Full Text-PDF Version (54 kB)
Michelle L. McCaskill, Edward O. Mason, Sheldon L. Kaplan, Wendy Hammerman, Linda B. Lamberth, Kristina G. Hultén. (2008) Increase of the USA300 Clone Among Community-Acquired Methicillin-Susceptible Staphylococcus aureus Causing Invasive Infections. The Pediatric Infectious Disease Journal 26:12, 1122-1127
Online publication date: 1-Jan-2008.
CrossRef
Stephanie M. Hamilton, Amy E. Bryant, Karen C. Carroll, Vivian Lockary, Yongsheng Ma, Eric McIndoo, Loren G. Miller, Francoise Perdreau‐Remington, John Pullman, George F. Risi, Daniel B. Salmi, and Dennis L. Stevens. (2007) In Vitro Production of Panton‐Valentine Leukocidin among Strains of Methicillin‐Resistant Staphylococcus aureus Causing Diverse Infections. Clinical Infectious Diseases 45:12, 1550-1558
Online publication date: 15-Dec-2007.
Abstract-Full Text-PDF Version (394 kB)
Susan I Gerber. (2006) Describing the methicillin-resistant <i>Staphylococcus aureus</i> epidemic: a public health challenge. Expert Review of Anti-infective Therapy 4:6, 905
CrossRef
Back to Top
Close Popup