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1 October 2006

Volume 43, Number 7
Clinical Infectious Diseases 2006;43:892–895
1058-4838/2006/4307-0014$15.00
DOI: 10.1086/507034
BRIEF REPORT

Primary Epstein‐Barr Virus Infection with Pneumonia Transmitted by Allogeneic Bone Marrow after Transplantation

Pierre Teira,1

Felix Agbalika,2

Anne Bergeron,3

Françoise Bernaudin,1

Maryvonnick Carmagnat,4

Régis Peffault de Latour,1

Vanderson Rocha,1

Agnès Devergie,1

Claire Rabian,4

Eliane Gluckman,1

Patricia Ribaud,1

Gérard Socié,1 and

Marie Robin1

1Service d’Hématologie–Allogreffe, 2Laboratoire de Virologie, 3Service de Pneumologie, and 4Laboratoire immunologie et histocompatibilité, Hôpital Saint Louis, Assistance Publique Hôpitaux de Paris, Paris, France

We report a case of primary Epstein‐Barr virus infection with lung involvement occurring 1 month after bone marrow transplantation. The transplant recipient had serological test results that were negative for Epstein‐Barr virus before transplantation. The virus must have been transmitted by the donor’s bone marrow, which was positive for Epstein‐Barr virus. The patient recovered after rituximab and corticosteroid therapy.

Received 3 March 2006; accepted 16 May 2006; electronically published 28 August 2006.

  • (See the editorial commentary by Bitan on pages 896–7)

Reprints or correspondence: Dr. Marie Robin, Service d’Hématologie–Allogreffe, Hôpital Saint Louis, 1 Ave. Claude Vellefaux, Paris, France ().

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Leonardo Potenza, Patrizia Barozzi, Mauro Codeluppi, Monica Morselli, Fabio Forghieri, Francesco Volzone, Giovanni Riva, Paola Pietrosemoli, Monica Pecorari, Giovanna Leonardi, Giuseppe Torelli, Mario Luppi. (2007) Epstein-Barr virus associated pneumonia in an adult patient with severe aplastic anaemia: Resolution after the transient withdrawal of cyclosporine. American Journal of Hematology 82:10, 944-946
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Menachem Bitan. (2006) Editorial Commentary: Epstein-Barr Virus Infection after Stem Cell Transplantation: New Concepts Are Needed Both for the Donor and the Recipient. Clinical Infectious Diseases 43:7, 896-897
Online publication date: 1-Oct-2006.
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