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NHSN Annual Update:
Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections

Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007

Antimicrobial-resistant pathogens that cause healthcare-associated infections (HAIs) pose an ongoing and increasing challenge to hospitals, both in the clinical treatment of patients and in the prevention of the cross-transmission of these problematic pathogens.  Describing the magnitude of the problem with respect to these antimicrobial-resistant pathogens is challenging, because the levels of antimicrobial resistance vary for different types of healthcare facilities and for different geographic areas, and some resistance phenotypes are difficult for laboratories to detect. However, the findings from such attempts may help the infection control and public health communities target problems and utilize resources more efficiently.

In the News

Featured in The Times
"Ireland 'losing war' on superbug" February 15, 2009
Challenges of Implementing National Guidelines for the Control and Prevention of Methicillin‐Resistant Staphylococcus aureus Colonization or Infection in Acute Care Hospitals in the Republic of Ireland
Fidelma Fitzpatrick, MD; Fiona Roche, PhD; Robert Cunney, MB; Hilary Humphreys, MD; Strategy for the Control of Antimicrobial Resistance in Ireland Infection Control Subcommittee
The research, published in Infection Control and Hospital Epidemiology, found one third of hospitals did not have a written policy on antibiotic use, and only 35% had an antibiotic stewardship programme.

February 2006

Volume 27, Number 2
Infect Control Hosp Epidemiol 2006;27:188–190
0899-823X/2006/2702-0013$15.00
DOI: 10.1086/500620
CONCISE COMMUNICATION

Biofilm Formation by and Accessory Gene Regulator Typing of Methicillin‐Resistant Staphylococcus aureus Strains Recovered From Patients With Nosocomial Infections

Kunihiro Manago, MD;

Junichiro Nishi, MD;

Naoko Wakimoto, MSc;

Hiroaki Miyanohara, MT;

Jav Sarantuya, MD;

Koichi Tokuda, MD;

Mayumi Iwashita, MD;

Kimie Yamamoto, MD;

Masao Yoshinaga, MD;

Ikuro Maruyama, MD;

Yoshifumi Kawano, MD

Drs. Manago, Nishi, Wakimoto, Sarantuya, Tokuda, Iwashita, Yamamoto, Yoshinaga, and Kawano are from the Department of Pediatrics, and Dr. Maruyama is from the Department of Laboratory and Molecular Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. Mr. Miyanohara is from the Clinical Laboratory of Kagoshima University Hospital, Kagoshima.

The association between biofilm formation and the accessory gene regulator (agr) types of methicillin‐resistant Staphylococcus aureus (MRSA) strains in our hospital were investigated. The biofilm index and the incidence of MRSA strains carrying agr‐2 in the infection group ( ) were significantly higher than were those in the carrier group ( ), suggesting that biofilm formation and agr type are associated with nosocomial MRSA infections.

Received March 13, 2004; accepted February 7, 2005; electronically published February 8, 2006.

Address requests for reprints to Junichiro Nishi, Dept. of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, 8‐35‐1 Sakuragaoka, Kagoshima 890‐8520, Japan ().

Cited by

A. Molina, R. Del Campo, L. Maiz, M.-I. Morosini, A. Lamas, F. Baquero, R. Canton. (2008) High prevalence in cystic fibrosis patients of multiresistant hospital-acquired methicillin-resistant Staphylococcus aureus ST228-SCCmecI capable of biofilm formation. Journal of Antimicrobial Chemotherapy 62:5, 961-967
Online publication date: 18-Aug-2008.
CrossRef
Hee Jung Yoon, Jun Yong Choi, Kyungwon Lee, Dongeun Yong, June Myung Kim, Young Goo Song. (2007) Accessory Gene Regulator Group Polymorphisms in Methicillin-Resistant Staphylococcus aureus: An Association with Clinical Significance. Yonsei Medical Journal 48:2, 176
Online publication date: 1-Feb-2007.
CrossRef
  • This study was financially supported by the Research Fund of the Ministry of Education, Culture, Sports, Science and Technology, Japan (grant 12470168).

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