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1 February 2006

Volume 42, Number 3
Clinical Infectious Diseases 2006;42:389–391
1058-4838/2006/4203-0015$15.00
DOI: 10.1086/499367
BRIEF REPORT

Changes in the Epidemiology of Methicillin‐Resistant Staphylococcus aureus in Intensive Care Units in US Hospitals, 1992–2003

R. Monina Klevens,1

Jonathan R. Edwards,1

Fred C. Tenover,1

L. Clifford McDonald,1

Teresa Horan,1

Robert Gaynes,1,2 and the

National Nosocomial Infections Surveillance System

1Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, and 2Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia

The proportion of Staphylococcus aureus isolates that were methicillin resistant (MRSA) increased from 35.9% in 1992 to 64.4% in 2003 for hospitals in the National Nosocomial Infections Surveillance system. During the same period, there was a decrease in resistance rates for several non–β‐lactam drugs among the MRSA isolates.

Received 14 September 2005; accepted 28 October 2005; electronically published 19 December 2005.

Reprints or correspondence: Dr. R. Monina Klevens, Div. of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd. (A‐24), Atlanta, GA 30333 ().

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