All Journals > Clinical Infectious Diseases > 15 December 2005 > Reemergence of Monkeypox

Article Tools

Search for Related Articles

  • By Author
  • Search In

Announcements

CID LISTED AMONG
“MOST INFLUENTIAL”

Clinical Infectious Diseases has been named as one of the "100 Most Influential Journals in Biology and Medicine" of the past 100 years by the Special Libraries Association. The list was compiled by the 680-plus members of SLA’s Biomedical and Life Sciences Division.

See the full list here.

Source: The DBIO 100, the 100 Most Influential Journals in Biology & Medicine over the last 100 Years

In the News

Featured in MSNBC
"Germs and flu are up; infection control is down" June 9, 2009
Trends in the Incidence of Methicillin‐Resistant Staphylococcus aureus Infection in Children’s Hospitals in the United States
Jeffrey S. Gerber, Susan E. Coffin, Sarah A. Smathers, and Theoklis E. Zaoutis
Just this week, researchers reported that the incidence of MRSA infections among children admitted to pediatric hospitals in the United States more than tripled between 2002 and 2007. Researchers at the Children’s Hospital of Philadelphia and the University of Pennsylvania found cases of MRSA jumped from 6.7 per 1,000 admissions in 2002 to 21.1 cases per 1,000 admissions in 2007, according to a study released online Monday in the journal Clinical Infectious Diseases.

Featured in Toronto Star
"Pigs, viruses and politics" May 2, 2009
Are Swine Workers in the United States at Increased Risk of Infection with Zoonotic Influenza Virus?
Kendall P. Myers, Christopher W. Olsen, Sharon F. Setterquist, Ana W. Capuano, Kelley J. Donham, Eileen L. Thacker, James A. Merchant, and Gregory C. Gray
Another study, this one published in the U.S. journal Clinical Infectious Diseases in 2006, found that workers in meat-processing plants have a greater likelihood of being infected by some version of the H1N1 flu virus than the general population (the odds of pig farmers getting the disease are significantly greater again).

Featured in Philadelphia Inquirer
"A shot in the arm for vaccines" April 19, 2009
Vaccines: Pneumococcal Vaccination of Elderly Adults: New Paradigms for Protection
Lisa A. Jackson and Edward N. Janoff
Every year, an estimated 915,000 people 65 and older get pneumonia, and 40 percent of them end up in hospitals, according to a 2004 paper in the journal Clinical Infectious Diseases. Pneumonia often kills older people, said Richard Stefanacci, a geriatrician at the University of the Sciences in Philadelphia.

15 December 2005

Volume 41, Number 12
Clinical Infectious Diseases 2005;41:1765–1771
© 2005 by the Infectious Diseases Society of America. All rights reserved.
1058-4838/2005/4112-0014$15.00
DOI: 10.1086/498155
HEALTHCARE EPIDEMIOLOGY INVITED ARTICLE

Reemergence of Monkeypox: Prevalence, Diagnostics, and Countermeasures

Aysegul Nalca,1

Anne W. Rimoin,2

Sina Bavari,1 and

Chris A. Whitehouse1

1United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland; and 2Department of Epidemiology, University of California–Los Angeles School of Public Health, Los Angeles

Human monkeypox is a viral zoonotic disease that occurs mostly in the rain forests of central and western Africa. However, the disease recently emerged in the United States in imported wild rodents from Africa. Monkeypox has a clinical presentation very similar to that of ordinary forms of smallpox, including flulike symptoms, fever, malaise, back pain, headache, and characteristic rash. Given this clinical spectrum, differential diagnosis to rule out smallpox is very important. There are no licensed therapies for human monkeypox; however, the smallpox vaccine can protect against the disease. The discontinuation of general vaccination in the 1980s has given rise to increasing susceptibility to monkeypox virus infection in the human population. This has led to fears that monkeypox virus could be used as a bioterrorism agent. Effective prevention relies on limiting the contact with infected patients or animals and limiting the respiratory exposure to infected patients.

Received 1 June 2005; accepted 13 July 2005; electronically published 11 November 2005.

Reprints or correspondence: Dr. Aysegul Nalca, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Frederick, MD 21702 ().

Robert A. Weinstein, Section Editor

Cited by

Morgan Wilson, Nektarios Lountzis, Tammie Ferringer. (2009) Zoonoses of dermatologic interest. Dermatologic Therapy 22:4, 367-378
Online publication date: 1-Aug-2009.
CrossRef
Scott Parker, Lauren Handley, R Mark Buller. (2008) Therapeutic and prophylactic drugs to treat orthopoxvirus infections. Future Virology 3:6, 595-612
Online publication date: 1-Dec-2008.
CrossRef
C. Caillat, D. Topalis, L. A. Agrofoglio, S. Pochet, J. Balzarini, D. Deville-Bonne, P. Meyer. (2008) Crystal structure of poxvirus thymidylate kinase: An unexpected dimerization has implications for antiviral therapy. Proceedings of the National Academy of Sciences 105:44, 16900-16905
Online publication date: 30-Nov-2008.
CrossRef
R.-H. Xu, M. Cohen, Y. Tang, E. Lazear, J. C. Whitbeck, R. J. Eisenberg, G. H. Cohen, L. J. Sigal. (2008) The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination. Journal of Experimental Medicine 205:4, 981-992
Online publication date: 17-Apr-2008.
CrossRef
Bennett Lorber. (2007) Snakes, Sex, Sushi, Saunas, and Spinach. Infectious Diseases in Clinical Practice 15:4, 225-229
Online publication date: 1-Aug-2007.
CrossRef
Marianne M Stanford, Grant McFadden, Gunasegaran Karupiah, Geeta Chaudhri. (2007) Immunopathogenesis of poxvirus infections: forecasting the impending storm. Immunology and Cell Biology 85:2, 93-102
Online publication date: 1-Mar-2007.
CrossRef
Scott Parker, Anthony Nuara, R Mark L Buller, Denise A Schultz. (2007) Human monkeypox: an emerging zoonotic disease. Future Microbiology 2:1, 17-34
Online publication date: 1-Mar-2007.
CrossRef
Donald M. McLean. (2006) Vaccinia Complications and Methisazone Therapy. Clinical Infectious Diseases 42:11, 1653-1653
Online publication date: 1-Jun-2006.
Citation-Full Text-PDF Version (367 kB)

  • The opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the US Army.

Back to Top
Close Popup