Bacterial Interference for Prevention of Urinary Tract Infection: A Prospective, Randomized, Placebo‐Controlled, Double‐Blind Pilot Trial
1Michael E. Debakey Veterans Affairs Medical Center, 2Institute for Rehabilitation and Research, and 3Baylor College of Medicine, Houston, Texas
This prospective, randomized, placebo‐controlled, double‐blind pilot trial examined the efficacy of bacterial interference in preventing urinary tract infection (UTI) in 27 patients with spinal cord injury. Patients whose bladders became colonized with Escherichia coli 83972 were half as likely (
) than noncolonized patients to develop UTI during the subsequent year.
Received 17 May 2005; accepted 6 July 2005; electronically published 13 October 2005.
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(See the editorial commentary by Ronald on pages 1535–6)
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