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1 September 2005 Supplement

Volume 192, Number S1
The Journal of Infectious Diseases 2005;192:S87–S93
© 2005 by the Infectious Diseases Society of America. All rights reserved.
0022-1899/2005/19205S1-0013$15.00
DOI: 10.1086/431508
SUPPLEMENT ARTICLE

Epidemiology and Burden of Rotavirus Diarrhea in Thailand: Results of Sentinel Surveillance

Chuleeporn Jiraphongsa,1

Joseph S. Bresee,9

Yaowapa Pongsuwanna,2

Pipat Kluabwang,3

Urai Poonawagul,4

Pramote Arporntip,5

Manas Kanoksil,6

Nakorn Premsri,7 and

Utcharee Intusoma,8 for the

Rotavirus Surveillance Project Thailand Study Groupa

1Bureau of Epidemiology, Ministry of Public Health, and 2National Institute of Health, Department of Medical Science, Nonthaburi, 3Maesod Hospital, Tak Province, 4Prapokklao Hospital, Chanthaburi Province, 5Hadyai Hospital, Songkhla Province, 6Nongkhai Hospital, Nongkhai Province, 7Sakaeo Hospital, Sakaeo Province, and 8Ramathibodi Hospital, Bangkok, Thailand; 9National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia

Diarrhea remains an important cause of morbidity and mortality among children in Thailand, with >1 million cases reported in 2002. In anticipation of the development of vaccines against rotavirus, we evaluated the disease burden associated with rotavirus infection in Thai children and evaluated the rotavirus serotypes now circulating in Thailand. Diarrhea surveillance was conducted at 6 Thai hospitals in different geographic areas. Community‐based surveillance was conducted in Huaykrajao District, Kanchanaburi Province. During the 24 months of surveillance, 4057 children were admitted to the 6 participating hospitals, and 1950 stool samples were collected. Of these stool samples, 43% (838) were positive for rotavirus. All rotavirus‐positive stool samples were evaluated to identify their serotypes; 54.8% of samples were of serotype G9, which was predominant each year. Other identified rotavirus serotypes included G2, G4, G1, and G3 (17.2%, 5.3%, 0.8%, and 0.1% of isolates, respectively). Approximately one‐half of the children hospitalized with rotavirus diarrhea were <1 year old. Community surveillance showed the proportion of cases of rotavirus diarrhea in the community to be much lower than that in the hospitalized population (12.2% vs. 43.0%).

Reprints or correspondence: Dr. Chuleeporn Jiraphongsa, Bureau of Epidemiology, Ministry of Public Health, Tiwanon Rd., Muang District, Nonthaburi, Thailand 11000 ().

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Online publication date: 1-Sep-2005.
Abstract-Full Text-PDF Version (133 kB)

  • Presented in part: Third Workshop of the Asian Rotavirus Surveillance Network, Manila, The Philippines, October 2003 (abstracts not published).

    Financial support: Vaccine Program at Program for Appropriate Technology in Health (PATH; Cooperative Arrangement 00‐GAT.770‐790‐01139‐COP).

    Potential conflicts of interest: none reported.

    The views expressed herein do not necessarily reflect the views of PATH or of the Bill and Melinda Gates Foundation.

  • Study group members are listed after the text.

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