All Journals > The Journal of Infectious Diseases > 1 June 2005 > Treatment of Otitis Media with Volatile Fluids

Article Tools

Search for Related Articles

  • By Author
  • Search In

Announcements

JID article wins Shepard Award

Congratulations to Joseph Igietseme Joseph U. Igietseme, Qing He, Kahaliah Joseph, Francis O. Eko, Deborah Lyn, Godwin Ananaba, Angela Campbell, Claudiu Bandea, and Carolyn M. Black.  Their JID article "Role of T lymphocytes in the pathogenesis of Chlamydia disease" has received the CDC's prestigious Charles C. Shepard Award. The award honors the most outstanding peer-reviewed research paper published by CDC scientists during the preceding year.

Click here to read the article.

Press Release

Preventive Behaviors Limited Household Transmission of H1N1 Influenza During Initial Outbreak

Maternal HIV-1 Treatment Protects Against Transmission to Newborns

In the News

Featured in Reuters
"Experimental flu treatment may help related virus" June 21, 2010
Reuters covers an experimental flu treatment described by Dr. Anne Moscona et. al.

Featured in Reuters
"Rotavirus vaccine keeps kids out of the hospital" May 17, 2010
Amy Norton covers Aaron T. Curns, et al.'s study about the Rotavirus Vaccine's effectiveness in preventing children from needing hospitalization. 

Featured in MSN
"Rotavirus Vaccine Helps Kids Avoid Severe Gastro Illness" May 12, 2010
Randy Dotinga covers Aaron T. Curns, et al.'s study about the Rotavirus Vaccine helping children to avoid gastoenteritis.

Featured in Los Angeles Times
"Rotavirus vaccines reduce hospitalizations in kids, study finds" May 12, 2010
Thomas H. Maugh II reports on Aaron T. Curns, et al.'s study about the postive effects of the Rotavirus Vaccine.

1 June 2005

Volume 191, Number 11
The Journal of Infectious Diseases 2005;191:1876–1880
© 2005 by the Infectious Diseases Society of America. All rights reserved.
0022-1899/2005/19111-0014$15.00
DOI: 10.1086/430003
BRIEF REPORT

Effective Treatment of Experimental Acute Otitis Media by Application of Volatile Fluids into the Ear Canal

Karl G. Kristinsson,1

Anna B. Magnusdottir,2

Hannes Petersen,2 and

Ann Hermansson3

Departments of 1Clinical Microbiology and 2ENT, Landspitali University Hospital, Reykjavik, Iceland; 3Department of Ear, Nose, and Throat, Lund University Hospital, Lund, Sweden

Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil (Ocimum basilicum) and essential oil components (thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%–81% of rats infected with H. influenzae and 6%–75% of rats infected with pneumococci, compared with 5.6%–6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media.

Received 11 August 2004; accepted 12 January 2005; electronically published 29 April 2005.

Reprints or correspondence: Prof. Karl G. Kristinsson, Dept. of Clinical Microbiology, Landspitali University Hospital, Hringbraut, 101 Reykjavik, Iceland ().

Cited by

Keith Singletary. (2010) Oregano. Nutrition Today 45:3, 129-138
Online publication date: 1-May-2010.
CrossRef
A. Nostro, A. Marino, A. R. Blanco, L. Cellini, M. Di Giulio, F. Pizzimenti, A. S. Roccaro, G. Bisignano. (2009) In vitro activity of carvacrol against staphylococcal preformed biofilm by liquid and vapour contact. Journal of Medical Microbiology 58:6, 791-797
Online publication date: 1-Jun-2009.
CrossRef

  • Financial support: Auris Ehf.

    Potential conflict of interest: K.G.K. is a shareholder in Auris Ehf, which funded the study.

Back to Top
Close Popup