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15 February 2005

Volume 40, Number 4
Clinical Infectious Diseases 2005;40:546–553
1058-4838/2005/4004-0009$15.00
DOI: 10.1086/427500
MAJOR ARTICLE

A Multifaceted Intervention to Improve Antimicrobial Prescribing for Upper Respiratory Tract Infections in a Small Rural Community

Michael A. Rubin,1

Kim Bateman,3

Stephen Alder,2

Sharon Donnelly,3

Gregory J. Stoddard,1 and

Matthew H. Samore1

Departments of 1Internal Medicine and 2Family and Preventive Medicine, University of Utah, and 3HealthInsight, Salt Lake City, Utah

Background.Antibiotic prescribing for upper respiratory tract infections (URTIs) is widespread, is often inappropriate, and may contribute to antibiotic resistance among community‐acquired pathogens, such as Streptococcus pneumoniae.

Methods.A multifaceted intervention involving health care professionals and patients was introduced to a small rural Utah community and included the repetitive use of printed diagnostic and treatment algorithms by professionals. Data on the quantity and class of antibiotic prescribing, which were collected from multiple sources, were measured for the intervention period (from January through June) in 2001 and compared with data for the baseline period during the same months in 2000.

Results.Medicaid claims data revealed that the percentage of patients in the community who received antibiotics for URTIs during the intervention period was 15.6% less than that for the baseline period, whereas the percentage in the rest of rural Utah was relatively stable, with a 1.5% decrease ( ). The greatest impact of the intervention was on prescribing for acute bronchitis (decreases of 56.1% and 1.7% in the community and rural Utah, respectively; ) and on prescribing of macrolides (decreases of 13.4% and 0.2% in the community and rural Utah, respectively; ). Community pharmacy data likewise revealed a 17.5% decrease in the rate of antibiotic prescribing during the intervention period ( ), with the largest decrease observed for macrolide prescribing (50.9%; ). Chart review data, in contrast, revealed no significant decrease in the percentage of patients with URTI who were prescribed an antibiotic (3.8%; ), although there was a significant decrease of 11.2% in macrolide use ( ).

Conclusions.A multifaceted intervention involving the repetitive use of printed algorithms resulted in modest improvements in antibiotic prescribing for outpatient URTIs, although one data source did not corroborate this. However, macrolide prescribing decreased sharply, irrespective of the source of data.

Received 14 June 2004; accepted 12 October 2004; electronically published 25 January 2005.

Reprints or correspondence: Dr. Michael A. Rubin, Div. of Clinical Epidemiology, Dept. of Internal Medicine, University of Utah School of Medicine, 300 N. 1900 East, Rm. AC‐230A, Salt Lake City, UT 84132 ().

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