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15 January 2005

Volume 40, Number 2
Clinical Infectious Diseases 2005;40:e16–e18
1058-4838/2005/4002-00E3$15.00
DOI: 10.1086/427034
BRIEF REPORT

Seroprevalence of Anti‐H5 Antibody among Thai Health Care Workers after Exposure to Avian Influenza (H5N1) in a Tertiary Care Center

Anucha Apisarnthanarak,1

Steven Erb,5

Iain Stephenson,5

Jacqueline M. Katz,5

Malinee Chittaganpitch,3

Somchai Sangkitporn,3

Rungruang Kitphati,3

Pranee Thawatsupha,3

Sunthareeya Waicharoen,3

Uayporn Pinitchai,2

Piyaporn Apisarnthanarak,4

Victoria J. Fraser,6 and

Linda M. Mundy7

1Infectious Diseases Division and 2Intensive Care Unit, Thammasart University Hospital, Pratumthani, 3Department of Medical Science, National Institute of Health, Nonthaburi, and 4Department of Radiology, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand; 5Influenza Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; and 6Infectious Diseases Division, Washington University School of Medicine, and 7Saint Louis University School of Public Health, St. Louis, Missouri

After the initial atypical presentation of a patient with avian influenza (H5N1) infection, paired acute‐phase and convalescent‐phase serum samples obtained from 25 health care workers (HCWs) who were exposed to the patient were compared with paired serum samples obtained from 24 HCWs who worked at different units in the same hospital and were not exposed to the patient. There was no serologic evidence of anti‐H5 antibody reactivity or subclinical infection in either of the groups.

Received 23 August 2004; accepted 20 September 2004; electronically published 17 December 2004.

Reprints or correspondence: Dr. Anucha Apisarnthanarak, Faculty of Medicine, Thammasart University Hospital, Klong Luang, Pratumthani, Thailand 12120 ().

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